Wiring and rewiring of the retinogeniculate synapse

被引:84
|
作者
Hong, Y. Kate [1 ]
Chen, Chinfei [1 ]
机构
[1] Harvard Univ, Childrens Hosp, Sch Med, Dept Neurol,FM Kirby Neurobiol Ctr, Boston, MA 02115 USA
关键词
LATERAL GENICULATE-NUCLEUS; MHC CLASS-I; PATTERNED RETINAL ACTIVITY; AMPA RECEPTOR TRAFFICKING; DEVELOPING VISUAL-SYSTEM; EYE-SPECIFIC SEGREGATION; EPHRIN-AS; PRENATAL DEVELOPMENT; NEURAL CIRCUITS; MICE LACKING;
D O I
10.1016/j.conb.2011.02.007
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The formation and refinement of synaptic circuits are areas of research that have fascinated neurobiologists for decades. A recurrent theme seen at many CNS synapses is that neuronal connections are at first imprecise, but refine and can be rearranged with time or with experience. Today, with the advent of new technologies to map and monitor neuronal circuits, it is worthwhile to revisit a powerful experimental model for examining the development and plasticity of synaptic circuits the retinogeniculate synapse.
引用
收藏
页码:228 / 237
页数:10
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