The tension rises in leukocyte extravasation

被引：0
|
作者：
Hordijk, Peter L. [1 ]
机构：
[1] Vrije Univ Amsterdam, Amsterdam, Netherlands
来源：
BLOOD | 2022年 / 140卷 / 03期
关键词：
MIGRATION;
D O I：
10.1182/blood.2022016596
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this issue of Blood, Wang et al(1) identified a critical role for the tension-sensitive cation channel PIEZO1 in leukocyte transendothelial migration (aka diapedesis or extravasation). Their detailed analysis provides new mechanistic data to fit the PIEZO1-mediated calcium influx into a sequence of endothelial signaling events that controls the extravasation process (see figure).
引用
收藏
页码：165 / 166
页数：2
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