ATIA: A Link between Inflammation and Hypoxia

被引：1
|
作者：
Lin, Anning [1 ,2 ]
机构：
[1] Univ Chicago, Ben May Dept Canc Res, Chicago, IL 60637 USA
[2] Chinese Acad Sci, Inst Biochem & Cell Biol, Shanghai 200031, Peoples R China
来源：
MOLECULAR CELL | 2011年 / 42卷 / 05期
关键词：
NF-KAPPA-B; CELL-DEATH; JNK ACTIVATION; INDUCTION;
D O I：
10.1016/j.molcel.2011.05.023
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Molecular Cell, Choksi et al. (2011) report the identification of an NF-kappa B-independent ATIA (anti-TNF alpha-induced apoptosis)-Thioredoxin 2 axis that inhibits TNF alpha- and hypoxia-induced apoptosis through elimination of excessive reactive oxygen species directly.
引用
收藏
页码：557 / 558
页数：2
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