Noninvasively measuring oxygen saturation of human finger-joint vessels by multi-transducer functional photoacoustic tomography

被引：30

作者：

Deng, Zijian ^{[1
]}

Li, Changhui ^{[1
]}

机构：

[1] Peking Univ, Dept Biomed Engn, Coll Engn, 5 Yiheyuan Rd, Beijing 100871, Peoples R China

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2016年 / 21卷 / 06期

基金：

美国国家科学基金会;

关键词：

photoacoustic tomography; human finger joints; oxygen saturation; medical imaging; EARLY RHEUMATOID-ARTHRITIS; BONE EROSIONS; ANGIOGENESIS; ULTRASONOGRAPHY; WRIST; MRI;

D O I：

10.1117/1.JBO.21.6.061009

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Imaging small blood vessels and measuring their functional information in finger joint are still challenges for clinical imaging modalities. In this study, we developed a multi-transducer functional photoacoustic tomography (PAT) system and successfully imaged human finger-joint vessels from similar to 1 mm to < 0.2 mm in diameter. In addition, the oxygen saturation (SO2) values of these vessels were also measured. Our results demonstrate that PAT can provide both anatomical and functional information of individual finger-joint vessels with different sizes, which might help the study of finger-joint diseases, such as rheumatoid arthritis. (C) 2016 Society of Photo-Optical Instrumentation Engineers (SPIE).

引用

页数：5