Surfactant-assisted synthesis of water-soluble and biocompatible semiconductor quantum dot micelles

被引：220
|
作者：
Fan, HY [1 ]
Leve, EW
Scullin, C
Gabaldon, J
Tallant, D
Bunge, S
Boyle, T
Wilson, MC
Brinker, CJ
机构：
[1] Sandia Natl Labs, Chem Synth & Nanomat Dept, Albuquerque, NM 87106 USA
[2] Univ New Mexico, NSF Ctr MicroEngineered Mat, Dept Chem & Nucl Engn, Albuquerque, NM 87131 USA
[3] Univ New Mexico, Sch Med, Dept Neurosci, Albuquerque, NM 87106 USA
来源：
NANO LETTERS | 2005年 / 5卷 / 04期
关键词：
D O I：
10.1021/nl050017l
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a simple, rapid approach to synthesize water-soluble and biocompatible fluorescent quantum dot (QD) micelles by encapsulation of monodisperse, hydrophobic QDs within surfactant/lipid micelles. Analyses of UV-vis and photo luminescence spectra, along with transmission electron microscopy, indicate that the water-soluble semiconductor QD micelles are monodisperse and retain the optical properties of the original hydrophobic QDs. The QD micelles were shown to be biocompatible and exhibited little or no aggregation when taken up by cultured rat hippocampal neurons.
引用
收藏
页码：645 / 648
页数：4
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