Methods for production of uniform small-sized polymersome with rigid membrane

被引：33
|
作者：
Men, Yongjun [1 ]
Peng, Fei [1 ]
Tu, Yingfeng [1 ]
van Hest, Jan C. M. [1 ]
Wilson, Daniela A. [1 ]
机构：
[1] Radboud Univ Nijmegen, Inst Mol & Mat, Heyendaalseweg 135, NL-6525 AJ Nijmegen, Netherlands
来源：
POLYMER CHEMISTRY | 2016年 / 7卷 / 24期
基金：
欧洲研究理事会;
关键词：
BLOCK-COPOLYMERS; DIBLOCK COPOLYMERS; VESICLES; NANOREACTOR; PERMEABILITY; STOMATOCYTES; DELIVERY; RELEASE; TUMOR; WATER;
D O I：
10.1039/c6py00668j
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
We report a facile methodology for the formation of uniform small-sized poly(ethylene glycol)-block-polystyrene (PEG-b-PS) polymersomes, via extrusion and sonication methods by using organic solvent as plasticizing agent. The obtained polymersomes have diameters less than 100 nm. The size and size distribution depend on the organic solvent content and sonication time. The small-sized polymersomes are able to carry both hydrophobic and hydrophilic dyes.
引用
收藏
页码：3977 / 3982
页数：6
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