Soluble Epoxide Hydrolase Inhibitor C-Aucb Decreases Blood Pressure and Attenuates the Activity of Renin-Angiotensin System in Cyp1a1-Ren-2 Transgenic Rats in Dose-Dependent Manner

被引：0
|
作者：
Sporkova, Alexandra [1 ]
Kopkan, Libor [1 ]
Huskova, Zuzana [1 ]
Vojtiskova, Alzbeta [1 ]
Hammock, Bruce D. [2 ]
Imig, John D. [3 ]
Cervenka, Ludek [1 ]
机构：
[1] Inst Clin & Expt Med, Prague, Czech Republic
[2] Univ Calif Davis, Davis, CA 95616 USA
[3] Med Coll Wisconsin, Madison, WI USA
来源：
HYPERTENSION | 2010年 / 56卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
引用
收藏
页码：E123 / E123
页数：1
相关论文
共 25 条
  • [1] Soluble epoxide hydrolase inhibition attenuates the development of hypertension in Cyp1a1-Ren-2 transgenic rats
    Kopkan, Libor
    Kramer, Herbert J.
    Huskova, Zuzana
    Vanourkova, Zdenka
    Vaneckova, Ivana
    Imig, John D.
    Hwang, Sung H.
    Hammock, Bruce D.
    Mullins, John J.
    Cervenka, Ludek
    HYPERTENSION, 2007, 50 (04) : E84 - E84
  • [2] Fenofibrate Attenuates Malignant Hypertension by Suppression of the Renin-angiotensin System: A Study in Cyp1a1-Ren-2 Transgenic Rats
    Jichova, Sarka
    Dolezelova, Sarka
    Kopkan, Libor
    Kompanowska-Jezierska, Elzbieta
    Sadowski, Janusz
    Cervenka, Ludek
    AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2016, 352 (06): : 618 - 630
  • [3] Inhibition of Soluble Epoxide Hydrolase Improves the Impaired Renal Autoregulation and Attenuates the Development of Angiotensin II-Dependent Malignant Hypertension in Cyp1a1-Ren-2 Transgenic Rats
    Honetschlaegerova, Zuzana
    Sporkov, Alexandra
    Kopkan, Libor
    Huskov, Zuzana
    Hwang, Sung H.
    Hammock, Bruce D.
    Imig, John D.
    Kramer, Herbert J.
    Eervenka, Ludik
    HYPERTENSION, 2010, 56 (05) : E158 - E158
  • [4] Renal mechanisms of antihypertensive effects caused by inhibition of soluble epoxide hydrolase in Cyp1a1-Ren-2 transgenic rats.
    Kopkan, Libor
    Honetschlagerova, Zuzana
    Huskova, Zuzana
    Imig, John D.
    Hwang, Sung H.
    Hammock, Bruce D.
    Cervenka, Ludek
    FASEB JOURNAL, 2009, 23
  • [5] SOLUBLE EPOXIDE HYDROLASE INHIBITION IMPROVES THE RENAL FUNCTION DURING THE DEVELOPMENT OF MALIGNANT HYPERTENSION IN CYP1A1-REN-2 TRANSGENIC RATS
    Honetschlagerova, Z.
    Imig, J. D.
    Hwang, S. H.
    Hammock, B. D.
    Cervenka, L.
    Kopkan, L.
    JOURNAL OF HYPERTENSION, 2010, 28 : E500 - E500
  • [6] Soluble Epoxide Hydrolase Inhibition Improves Renal Function During Development of Malignant Hypertension in Cyp1a1-Ren-2 Transgenic Rats
    Honetschlagerova, Zuzana
    Imig, John D.
    Hammock, Bruce D.
    Cervenka, Ludik
    Kopkan, Libor
    HYPERTENSION, 2009, 54 (04) : E66 - E66
  • [7] Breeding Characteristics and Dose-dependent Blood Pressure Responses of Transgenic Cyp1a1-Ren2 Rats
    Leader, Catherine J.
    Clark, Barbara J.
    Hannah, Amber R.
    Sammut, Ivan A.
    Wilkins, Gerard T.
    Walker, Robert J.
    COMPARATIVE MEDICINE, 2018, 68 (05) : 360 - 366
  • [8] Reversible cardiac remodeling after renin-angiotensin system stimulation in CYP1A1-Ren2 transgenic rats
    Janssen, Ben
    Heijnen, Bart
    Pelkmans, Leonie
    Danser, Jan
    Garrelds, Ingrid
    Mullins, John
    De Mey, Jo
    Struijker-Boudier, Harry
    FASEB JOURNAL, 2012, 26
  • [9] Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats
    Heijnen, Bart F. J.
    Pelkmans, Leonie P. J.
    Danser, A. H. Jan
    Garrelds, Ingrid M.
    Mullins, John J.
    De Mey, Jo G. R.
    Struijker-Boudier, Harry A. J.
    Janssen, Ben J. A.
    JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, 2014, 15 (01) : 69 - 81
  • [10] Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: Studies in Cyp1a1-Ren-2 transgenic rats
    Sporkova, Alexandra
    Jichova, Sarka
    Huskova, Zuzana
    Kopkan, Libor
    Nishiyama, Akira
    Hwang, Sung H.
    Hammock, Bruce D.
    Imig, John D.
    Kompanowska-Jezierska, Elzbieta
    Sadowski, Janusz
    Kramer, Herbert J.
    Cervenka, Ludek
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2014, 41 (12) : 1003 - 1013
123