Synthesis of trisubstituted 4-oxepanones by the Lewis acid-promoted three-component ring-expansion reaction of cyclopropapyranones, silyl enolates and glyoxylates

被引：9
|
作者：
Sugita, Y [1 ]
Kimura, C [1 ]
Yokoe, I [1 ]
机构：
[1] Josai Univ, Fac Pharmaceut Sci, Sakado, Saitama 3500295, Japan
来源：
HETEROCYCLES | 2001年 / 55卷 / 05期
关键词：
cyclopropane; oxepane Zwitterion; Lewis acid;
D O I：
10.3987/COM-01-9192
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In the presence of SnCl4, cyclopropapyranones easily reacted with silyl enolates and ethyl glyoxylate to give the trisubstituted 4-oxepanones in good yields.
引用
收藏
页码：855 / 859
页数：5
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