Promising immunologic findings with impacts on systemic therapy of atopic dermatitis

被引：0
|
作者：
Wagenknecht, S. [1 ]
Roesner, L. M. [1 ]
Mommert, S. [1 ]
Schaper-Gerhardt, K. [1 ]
Zeitvogel, J. [1 ]
Werfel, T. [1 ]
机构：
[1] Hannover Med Sch, Abt Immundermatol & Allergol, Klin Dermatol Allergol & Venerol, Hannover, Germany
来源：
DERMATOLOGIE IN BERUF UND UMWELT | 2020年 / 68卷 / 01期
关键词：
atopic dermatitis; anti-microbial peptides; microbiome; histamine; GATA3; ANTIMICROBIAL PEPTIDES; MALASSEZIA-SYMPODIALIS; SKIN MICROBIOME; EXPRESSION; KERATINOCYTES; INFLAMMATION; IGE;
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Atopic dermatitis (AD) is a complex disease which is, to date, neither properly investigated nor fully understood. The following article emphasizes factors which are focused in current research projects on AD which affect the pathogenesis of AD essentially. These factors comprise antimicrobial peptides, the cutaneous microbiome, importance of the histamine receptor H4R, and genetic implications which provide relevant insights in implications for systemic therapies in AD treatment.
引用
收藏
页码：20 / 26
页数：7
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