Effect of integrated traditional Chinese medicine therapy in the treatment of children with dyspeptic diarrhea

Objective: To inquire into the effect of integrated traditional Chinese medicine (TCM) therapy on alleviating diarrhea and improving immune function in children with dyspeptic diarrhea. Methods: One hundred and seventy-three children with dyspeptic diarrhea treated in the Henan Provincial Hospital of Traditional Chinese Medicine from May 2017 to February 2019 were selected. 78 cases in the control group (CG) were given western medicine treatment, and 95 cases in the research group (RG) were given integrated TCM therapy. The symptom improvement time, clinical indicators and efficacy of the two groups were observed and recorded. The improvement of gastrointestinal function and the expression of inflammatory factors were measured before and after treatment. The trace element detector was utilized for trace element content detection, and FACSCalibo flow cytometry for the peripheral blood T lymphocyte subsets determination. Hamilton anxiety scale (HAMA) was used to evaluate the anxiety of the two groups before and after treatment. Results: RG showed evidently less recovery time and better clinical indexes than CG. The improvement of abdominal distension, abdominal pain and diarrhea was significantly better in RG than in CG. Compared with CG, the concentrations of motilin and gastrin were significantly lower in RG. The IL-6 and TNF-alpha levels in RG were significantly lower than those in CG. The improvement of trace elements and immune function in RG was significantly superior to that in CG. RG presented significantly lower HAMA scores and an evidently better total effective rate than CG. Conclusions: Integrated TCM therapy is a feasible treatment scheme for children with dyspeptic diarrhea. It can reduce the frequency of diarrhea, improve gastrointestinal function, reduce inflammatory factors and enhance the immune function of children.