Impact of UGT1A1 genotype on the efficacy and safety of irinotecan-based chemotherapy in metastatic colorectal cancer (mCRC): A preplanned analysis of the phase III AXEPT trial

被引:0
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作者
Xu, R. [1 ]
Muro, K. [2 ]
Kim, T. W. [3 ]
Park, Y. S. [4 ]
Wang, W. [5 ]
Han, S-W. [6 ]
Kotaka, M. [7 ]
Deng, Y-H. [8 ]
Ahn, J. B. [9 ]
Nakamura, M. [10 ]
Ba, Y. [11 ]
Cho, S-H. [12 ]
Kato, T. [13 ]
Zhang, T. [14 ]
Lee, K-W. [15 ]
Matsuoka, H. [16 ]
Fang, W-J. [17 ]
Morita, S. [18 ]
Iwasa, S. [19 ]
Junichi, S. [20 ]
机构
[1] Sun Yat Sen Univ, Dept Med Oncol, Ctr Canc, Guangzhou, Guangdong, Peoples R China
[2] Aichi Canc Ctr Hosp, Dept Clin Oncol, Nagoya, Aichi, Japan
[3] Univ Ulsan, Dept Oncol, Asan Med Ctr, Coll Med, Seoul, South Korea
[4] Samsung Med Ctr, Dept Med, Seoul, South Korea
[5] First Peoples Hosp Foshan, Dept Gastrointestinal Oncol, Foshan, Peoples R China
[6] Seoul Natl Univ Hosp, Internal Med, Seoul, South Korea
[7] Sano Hosp, Gastrointestinal Canc Ctr, Surg, Kobe, Hyogo, Japan
[8] Sun Yat Sen Univ, Affiliated Hosp 6, Dept Med Oncol, Guangzhou, Guangdong, Peoples R China
[9] Yonsei Univ, Severance Hosp, Dept Internal Med, Seoul, South Korea
[10] Aizawa Hosp, Aizawa Comprehens Canc Ctr, Matsumoto, Nagano, Japan
[11] Tianjin Med Univ, Canc Inst & Hosp, Dept Digest Oncol, Tianjin, Peoples R China
[12] Chonnam Natl Univ Hosp, Hematol Oncol, Gwanju, South Korea
[13] Natl Hosp Org Osaka Natl Hosp, Colorectal Surg, Osaka, Japan
[14] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Abdominal Oncol, Wuhan, Hubei, Peoples R China
[15] Seoul Natl Univ, Bundang Hosp, Coll Med, Internal Med, Seongnam, South Korea
[16] Fujita Hlth Univ Hosp, Surg, Toyoake, Aichi, Japan
[17] Zhejiang Univ, Affiliated Hosp 1, Dept Med Oncol, Hangzhou, Zhejiang, Peoples R China
[18] Kyoto Univ, Med Stat & Bioinformat, Kyoto, Japan
[19] Natl Canc Ctr, Dept Expt Therapeut, Tokyo, Japan
[20] Tokai Cent Hosp, Kakamigahara, Japan
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
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