Isolation and characterization of mouse hepatic stem cells in vitro

被引：8
|
作者：
Weiss, MC [1 ]
Strick-Marchand, H [1 ]
机构：
[1] Inst Pasteur, Dept Dev Biol, CNRS, Unite Genet Differenciat,URA 2578, F-75724 Paris 15, France
来源：
SEMINARS IN LIVER DISEASE | 2003年 / 23卷 / 04期
关键词：
hepatoblasts; oval cells; hepatocytes; cholangiocytes; DEVELOPING MURINE LIVER; TARGET GENE HNF-3-BETA; OVAL CELLS; BONE-MARROW; PROGENITOR CELLS; TRANSCRIPTION FACTORS; DIFFERENTIAL EXPRESSION; RAT-LIVER; WILD-TYPE; HEPATOCYTE;
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
This article covers mouse cell lines showing the properties of hepatoblasts or oval cells and describes hepatocyte differentiation obtained from embryonic stem (ES) cells and mesenchymal adult progenitor cells. It considers the methods used for cultivation and differentiation of the cells, as well as the strengths and weaknesses of the different systems and perspectives for future research. Emphasis is given to hepatoblast cell lines because this is the material for which bipotentiality has been most clearly demonstrated and for which proliferation and differentiation conditions have been worked out.
引用
收藏
页码：313 / 324
页数：12
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