Quantifying intraocular scatter with near diffraction-limited double-pass point spread function

被引：13
|
作者：
Zhao, Junlei [1 ,2 ,3 ]
Xiao, Fei [1 ,2 ]
Kang, Jian [1 ,2 ,3 ]
Zhao, Haoxin [1 ,2 ]
Dai, Yun [1 ,2 ]
Zhang, Yudong [1 ,2 ]
机构：
[1] Chinese Acad Sci, Key Lab Adapt Opt, Chengdu 610209, Peoples R China
[2] Chinese Acad Sci, Inst Opt & Elect, Lab Adapt Opt, Chengdu 610209, Peoples R China
[3] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
BIOMEDICAL OPTICS EXPRESS | 2016年 / 7卷 / 11期
基金：
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词：
RETINAL-IMAGE QUALITY; WAVE-FRONT SENSOR; LIGHT-SCATTERING; EYES; ABERRATIONS; INSTRUMENT; STRAYLIGHT; CATARACTS;
D O I：
10.1364/BOE.7.004595
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Measurement of the double-pass (DP) point-spread function (PSF) can provide an objective and non-invasive method for estimating intraocular scatter in the human eye. The objective scatter index (OSI), which is calculated from the DP PSF images, is commonly used to quantify intraocular scatter. In this article, we simulated the effect of higher-order ocular aberrations on OSI, and the results showed that higher-order ocular aberrations had a significant influence on OSI. Then we developed an adaptive optics DP PSF measurement system (AO-DPPMS) which was capable of correcting ocular aberrations up to eighth-order radial Zernike modes over a 6.0-mm pupil. Employing this system, we obtained DP PSF images of four subjects at the fovea. OSI values with aberrations corrected up to 2nd, 5th and 8th Zernike order were calculated respectively, from the DP PSF images of the four subjects. The experimental results were consistent with the simulation, suggesting that it is necessary to compensate for the higher-order ocular aberrations for accurate intraocular scatter estimation. (C) 2016 Optical Society of America
引用
收藏
页码：4595 / 4604
页数：10
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