Mobile digital x-ray and portable cartridge based nucleic acid amplification test machines for point-of-care diagnosis of TB in rural India

被引：1

作者：

Datta, Bornali ^{[1
]}

Ford, David ^{[2
]}

Goyal, Pinky ^{[1
]}

Prakash, Ashish ^{[1
]}

Tripathy, Jaya Prasad ^{[3
]}

Gnanashanmugam, Devasena ^{[4
]}

Mishra, Sunil ^{[1
]}

Aggarwal, Ankit ^{[1
]}

Kotalwar, Sameer Gopalrao ^{[1
]}

Mittal, Sandeep ^{[1
]}

Mangla, Anshul ^{[5
,6
]}

Jaiswal, Anand ^{[1
]}

Trehan, Naresh ^{[1
]}

机构：

[1] Medanta Medicity, Dept Resp Med, Gurgaon, Haryana, India

[2] Scarborough Gen Hosp, Dept Resp Med, Scarborough, England

[3] All India Inst Med Sci, Dept Community Med, Nagpur, Maharashtra, India

[4] Cepheid, Med Affairs, Washington, DC USA

[5] VMMC, Dept Pulm Crit Care & Sleep Med, New Delhi, India

[6] Safdarjang Hosp, New Delhi, India

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2021年 / 115卷 / 08期

关键词：

active case finding; CBNAAT Edge; digital chest x-ray; GeneXpert; point-of-care test; TUBERCULOSIS DIAGNOSIS;

D O I：

10.1093/trstmh/traa152

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: There is no experience of point-of-care (POC) microbiological confirmation for TB in India in field settings. Methods: Under the TB-Free Haryana project, a mobile van-mounted digital x-ray and portable GeneXpert system screened all presumptive TB patients with strong clinic-radiological suspicion for TB. Results: Of 1673 x-rays, 215 (13%) had findings suggestive of TB, 109 had strong clinical suspicion and were eligible for POC GeneXpert, in whom a test was performed in 82 (75%) cases; 59 (72%) tested positive and were initiated on treatment within 24 h. Conclusions: A mobile van equipped with digital x-ray and POC GeneXpert is feasible and has a good success rate with potential for replication.

引用

页码：937 / 939

页数：3

共 12 条

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