Therapeutic alternatives to surgical treatment of malignant eyelid tumors and their precursors

被引:0
|
作者
Girbardt, C. [1 ]
Moessner, A. [1 ]
Wiedemann, P. [1 ]
Grunewald, S. [2 ]
机构
[1] Univ Klinikum Leipzig AoR, Klin & Poliklin Augenheilkunde, Liebigstr 10-14, D-04103 Leipzig, Germany
[2] Univ Klinikum Leipzig AoR, Klin Dermatol Venerol & Allergol, Leipzig, Germany
来源
OPHTHALMOLOGE | 2020年 / 117卷 / 05期
关键词
Cryodestruction; Basal cell carcinoma; Squamous cell carcinoma; Precursor lesions; Systemic treatment; EPIDERMAL-GROWTH-FACTOR; BASAL-CELL CARCINOMA; RADIOTHERAPY; MANAGEMENT; CETUXIMAB; OPTIONS;
D O I
10.1007/s00347-020-01072-y
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
The treatment of choice for malignant eyelid tumors is surgical excision. If this is not feasible or undesirable, a number of alternative treatments are available. Possible systemic preparations are vismodegib and sonidegib for basal cell carcinoma as well as cetuximab and cemiplimab for squamous cell carcinoma. Cryodestruction is possible for superficial tumors. In situ findings can be treated with the local preparations imiquimod or 5-fluorouracil and with photodynamic therapy. An interdisciplinary cooperation with dermatologists is advisable.
引用
收藏
页码:478 / 483
页数:6
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