Machine learning approaches in Covid-19 severity risk prediction in Morocco

被引:30
|
作者
Laatifi, Mariam [1 ]
Douzi, Samira [2 ]
Bouklouz, Abdelaziz [3 ]
Ezzine, Hind [1 ]
Jaafari, Jaafar [4 ]
Zaid, Younes [1 ,5 ]
El Ouahidi, Bouabid [6 ]
Naciri, Mariam [1 ]
机构
[1] Mohammed V Univ, Dept Biol, Fac Sci, Rabat, Morocco
[2] Univ Mohammed 5, FMPR, Rabat, Morocco
[3] Fac Med & Pharm, Lab Pharmacol & Toxicol, Rabat, Morocco
[4] Univ Hassan 2, FSTM, Casablanca, Morocco
[5] Cheikh Zaid Hosp, Res Ctr Abulcasis Univ Hlth Sci, Rabat, Morocco
[6] Mohammed V Univ, Dept Comp Sci, Fac Sci, Rabat, Morocco
关键词
COVID-19; Severity; Machine learning; Feature selection; Feature reduction; Data analysis; CORONAVIRUS; PNEUMONIA; PROGNOSIS;
D O I
10.1186/s40537-021-00557-0
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
The purpose of this study is to develop and test machine learning-based models for COVID-19 severity prediction. COVID-19 test samples from 337 COVID-19 positive patients at Cheikh Zaid Hospital were grouped according to the severity of their illness. Ours is the first study to estimate illness severity by combining biological and non-biological data from patients with COVID-19. Moreover the use of ML for therapeutic purposes in Morocco is currently restricted, and ours is the first study to investigate the severity of COVID-19. When data analysis approaches were used to uncover patterns and essential characteristics in the data, C-reactive protein, platelets, and D-dimers were determined to be the most associated to COVID-19 severity prediction. In this research, many data reduction algorithms were used, and Machine Learning models were trained to predict the severity of sickness using patient data. A new feature engineering method based on topological data analysis called Uniform Manifold Approximation and Projection (UMAP) shown that it achieves better results. It has 100% accuracy, specificity, sensitivity, and ROC curve in conducting a prognostic prediction using different machine learning classifiers such as X_GBoost, AdaBoost, Random Forest, and ExtraTrees. The proposed approach aims to assist hospitals and medical facilities in determining who should be seen first and who has a higher priority for admission to the hospital.
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收藏
页数:21
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