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Non-viral, precisely engineered immune cells tested in lymphoma
被引:0
|作者:
Hu, Yongxian
[1
]
Zhang, Jiqin
[2
]
Eyquem, Justin
[3
]
机构:
[1] Zhejiang Univ, Sch Med, Hangzhou, Peoples R China
[2] East China Normal Univ, Shanghai, Peoples R China
[3] Univ Calif San Francisco, San Francisco, CA 94143 USA
关键词:
Cancer;
Therapeutics;
Drug discovery;
D O I:
10.1038/d41586-022-02272-z
中图分类号:
O [数理科学和化学];
P [天文学、地球科学];
Q [生物科学];
N [自然科学总论];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
An improved approach has been developed for producing precisely designed immune cells called CAR T cells that recognize and kill cancer cells. CAR T cells generated in this way were safe and showed potential therapeutic effects in individuals with a relapsed or treatment-resistant form of the immune-cell cancer called B-cell non-Hodgkin's lymphoma.
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