Palladium-Catalyzed Intermolecular Decarboxylative Coupling of 2-Phenylbenzoic Acids with Alkynes via C-H and C-C Bond Activation

被引：258
|
作者：
Wang, Congyang [1 ]
Rakshit, Souvik [1 ]
Glorius, Frank [1 ]
机构：
[1] Univ Munster, NRW Grad Sch Chem, Inst Organ Chem, D-48149 Munster, Germany
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 40期
关键词：
AROMATIC CARBOXYLATE SALTS; BENZOIC-ACIDS; DIRECT ARYLATION; ANNULATION; OLEFINATION; MECHANISM; DERIVATIVES; CLEAVAGE; INDOLES; ARENE;
D O I：
10.1021/ja106130r
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel protocol for palladium-catalyzed intermolecular formal [4 + 2] annulation of 2-phenylbenzoic acids with alkynes is described. Acridine is shown to be essential for the high reaction efficiency. Phenanthrene derivatives are formed in moderate to good yields without coupling (pseudo)halides or organometallic species.
引用
收藏
页码：14006 / 14008
页数：3
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