The significance of extended pelvic lymphadenectomy in bladder cancer

被引：0
|
作者：
Autenrieth, M. [1 ]
Retz, M. [1 ]
Gschwend, J. E. [1 ]
机构：
[1] Tech Univ Munich, Urol Klin & Poliklin, D-81675 Munich, Germany
来源：
UROLOGE | 2011年 / 50卷 / 12期
关键词：
Bladder cancer; Prognosis; Lymphadenectomy; Radical surgery; Risk of systemic progression; LYMPH-NODE DISSECTION; TRANSITIONAL-CELL CARCINOMA; RADICAL CYSTECTOMY; PROGNOSIS; SURGERY; ERA;
D O I：
10.1007/s00120-011-2665-9
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Despite radical surgery, invasive urothelial carcinoma has a high risk of systemic progression. This might be due to the presence of occult but already disseminated tumor cells in lymph nodes, blood, or bone marrow. In all retrospective series presented here, extended pelvic lymphadenectomy seems to provide a clear benefit for survival in pN0 and pN+ patients. Lymph node density and absolute number of positive lymph nodes appear to affect patient outcome and survival. However, only the randomized, prospective German LEA study will hopefully provide conclusive new data.
引用
收藏
页码：1591 / 1594
页数：4
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