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- [4] Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl)indolin-5-yl) thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraine EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 : 94 - 107
- [5] Discovery of Dual Inducible/Neuronal Nitric Oxide Synthase (iNOS/nNOS) Inhibitor Development Candidate 4-(2-Cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) Part 2: Identification of a Novel, Potent, and Selective Series of Benzimidazole-Quinolinone iNOS/nNOS Dimerization Inhibitors That Are Orally Active in Pain Models JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (21) : 7739 - 7755