Organ-specific management and supportive care in chronic graft-versus-host disease

被引：57

作者：

Dignan, Fiona L. ^{[1
,2
]}

Scarisbrick, Julia J. ^{[3
]}

Cornish, Jacqueline ^{[4
]}

Clark, Andrew ^{[5
]}

Amrolia, Persis ^{[6
]}

Jackson, Graham ^{[7
]}

Mahendra, Prem ^{[8
]}

Taylor, Peter C. ^{[9
]}

Shah, Pallav ^{[10
]}

Lightman, Sue ^{[11
]}

Fortune, Farida ^{[12
]}

Kibbler, Christopher ^{[13
]}

Andreyev, Jervoise ^{[14
]}

Albanese, Assunta ^{[15
]}

Hadzic, Nedim ^{[16
,17
]}

Potter, Michael N. ^{[1
]}

Shaw, Bronwen E. ^{[1
,18
]}

机构：

[1] Royal Marsden NHS Fdn Trust, Sect Haematooncol, London, England

[2] St Thomas Hosp, St Johns Inst Dermatol, London, England

[3] Univ Hosp Birmingham, Dept Dermatol, Birmingham, W Midlands, England

[4] Bristol Royal Hosp Children, Dept Haematol, Bristol, Avon, England

[5] Gartnavel Hosp, Beatson Oncol Ctr, Bone Marrow Transplant Unit, Glasgow, Lanark, Scotland

[6] Great Ormond St Hosp Sick Children, Dept Bone Marrow Transplantat, London, England

[7] Freeman Rd Hosp, Dept Haematol, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England

[8] Univ Hosp Birmingham, Dept Haematol, Birmingham, W Midlands, England

[9] Rotherham Gen Hosp, Dept Haematol, Rotherham, S Yorkshire, England

[10] Royal Brompton Hosp, Dept Resp Med, London SW3 6LY, England

[11] UCL, Inst Ophthalmol, Moorfields Eye Hosp, London, England

[12] Barts & London NHS Trust, Dept Oral Med, London, England

[13] Royal Free Hampstead NHS Trust, Dept Med Microbiol, London, England

[14] Royal Marsden NHS Fdn Trust, Dept Med, London, England

[15] St George Hosp, Paediat Endocrine Unit, London, England

[16] Kings Coll Hosp London, Paediat Liver Serv, London, England

[17] Kings Coll Hosp London, Inst Liver Studies, London SE5 8RX, England

[18] Anthony Nolan, London, England

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2012年 / 158卷 / 01期

关键词：

chronic; graft-versus-host disease; supportive care; transplant; STEM-CELL TRANSPLANTATION; BONE-MARROW-TRANSPLANTATION; CONSENSUS DEVELOPMENT PROJECT; WORKING GROUP-REPORT; LONG-TERM ACYCLOVIR; QUALITY-OF-LIFE; BRONCHIOLITIS OBLITERANS SYNDROME; DOUBLE-BLIND TRIAL; SERUM EYE DROPS; CYTOMEGALOVIRUS-INFECTION;

D O I：

10.1111/j.1365-2141.2012.09131.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A joint working group established by the Haemato-oncology subgroup of the British Committee for Standards in Haematology and the British Society for Bone Marrow Transplantation has reviewed the available literature and made recommendations for the supportive care and management of organ-specific complications of chronic graft-versus-host disease (cGvHD). This guideline includes recommendations for the specific therapy of skin, oral, liver, gut, lung, ocular and genital manifestations of cGvHD and for the supportive care of these patients, including vaccinations and prophylaxis against infection. The goal of treatment should be effective control of GvHD while minimizing the risk of toxicity and relapse.

引用

页码：62 / 78

页数：17

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