This paper presents a miniaturized design of a 2x zoom lens for application to a one-megapixel image sensor in a capsule endoscope. The zoom lens is composed of four lenses, including three plastic aspheric lenses and one glass spherical lens, and adopts a three-lens group design. This capsule endoscope is mainly for observation of the small intestine, which has a radius of about 12.5 mm. The height of the object is thus set to 12.5 mm. The object surface is designed to be curved surface with a radius of curvature of 15 mm. The focal length of the zoom lens ranges from 1.064 mm to 2.039 mm, and the full angle of view ranges from 60 degrees to 143 degrees, the f-number is F/2.8-F/3.5, the zoom lens is 11.6 mm in length, and the maximum effective diameter of the zoom lens is 6 mm. The zoom lens design is divided into six segments, corresponding to the different magnifications from Zoom 1 to Zoom 6. The magnification ratios are -0.0845, -0.0984, -0.1150, -0.1317, -0.1482, and -0.1690, respectively. Comparing the positions from Zoom 1 to Zoom 6, the maximum optical distortion is -14.89% for the Zoom 1 and 1.45% for the Zoom 6. The maximum vertical video distortion is 8.19% for Zoom 1 and 1.00% for Zoom 6. At a 1.0 field of view, the minimum relative illuminance is 71.8% at a magnification of M = -0.1317. Finally, we perform the tolerance analysis and lens resolution analysis at different zooming positions. Our design can obtain high-quality images for capsule endoscope.