More fuel for the fire: Gut microbes and toxicity to immune agonist antibodies in cancer

被引：1
|
作者：
Chelvanambi, Manoj [1 ]
Wargo, Jennifer A. [1 ,2 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Dept Surg Oncol, 1515 Holcombe Blvd, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Genom Med, 1515 Holcombe Blvd, Houston, TX 77030 USA
来源：
CELL REPORTS MEDICINE | 2021年 / 2卷 / 12期
关键词：
D O I：
10.1016/j.xcrm.2021.100482
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Microbes in the gut impact response, resistance, and toxicity to numerous cancer therapies, though mechanisms remain incompletely understood. Blake et al. provide further evidence that gut microbes promote toxicity to immune-agonistic antibodies, with opportunities to target these in cancer treatment.
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页数：3
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