Microwave assisted synthesis of 3,5-diaryl-6-carbetboxy cyclohex-2-en-1-ones on solventless inorganic solid support and their antibacterial activities

被引：0
|
作者：
Roy, Ravindra S. [1 ]
Chundawat, Jagveer S. [1 ]
Dulawat, Shiv S. [1 ]
机构：
[1] BNPG Coll, Dept Chem, Udaipur 313001, Raj, India
来源：
AFINIDAD | 2011年 / 68卷 / 555期
关键词：
antibacterial activity; basic alumina; chalcones; cyclohexenone; microwave irradiation; CHALCONES; PYRIMIDINES;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A variety of 3,5-diaryl-6-carbethoxy cyclohex-2-en-1-ones derivatives (4a-g) were synthesized by the reaction of ethylacetoacetate with substituted chalcones in conventional (acetone & anhy. K2CO3) and microwave assisted solution phase (acetone & anhy. K2CO3) and dry media (basic Al2O3/piperidine). From the comparative study we have concluded that efficient dry media synthesis of 3,5 diaryl-6-carbethoxy cyclohex-2-en-1-ones under microwave irradiation can be carried out in domestic microwave oven with enhanced reaction rates and improved yields. The structure of compounds are supported by spectral and analytical data. The structure activity relationship of synthesized compounds have also been studied.
引用
收藏
页码：389 / 393
页数：5
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