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- [6] Cyclin-dependent kinase 4/6 (CDK4/6) inhibitor SHR6390 combined with pyrotinib and letrozole in patients with human epidermal growth factor receptor 2-positive (HER2+), hormone receptor positive (HR plus ) metastatic breast cancer (MBC): Phase Ib study results. JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)