The use of novel photobleachable phthalocyanines to image DNA

被引：16
|
作者：
Turanli-Yildiz, Burcu [2 ,3 ]
Sezgin, Tugba [2 ,3 ]
Cakar, Z. Petek [2 ,3 ]
Uslan, Canan [1 ]
Sesalan, B. Sebnem [1 ]
Gul, Ahmet [1 ]
机构：
[1] Tech Univ Istanbul, Dept Chem, TR-34469 Istanbul, Turkey
[2] Tech Univ Istanbul, Dept Mol Biol & Genet, TR-34469 Istanbul, Turkey
[3] Tech Univ Istanbul, Dr Orhan Ocalgiray Mol Biol Biotechnol & Genet Re, TR-34469 Istanbul, Turkey
来源：
SYNTHETIC METALS | 2011年 / 161卷 / 15-16期
关键词：
DNA; Phthalocyanine; Water soluble; METAL-PORPHYRAZINE DERIVATIVES; CIRCULAR-DICHROISM; BINDING; ZINC; COMPLEXES; OXIDATION; POLYMERS; COBALT; RED;
D O I：
10.1016/j.synthmet.2011.06.012
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
The interaction of cationic photobleachable cobalt 1 and palladium 2 phthalocyanines (pcs) with calf thymus (CT) DNA was investigated by UV/vis spectrophotometric methods and gel electrophoresis. With the addition of pcs, the change in the thermal denaturation profile of DNA was observed. The results indicated that these molecules exhibit efficient DNA binding activity. The new cationic cobalt derivative 1 was characterized by elemental analysis, UV, IR and mass spectrophotometry. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码：1720 / 1724
页数：5
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