Eucalyptals A-C with a new skeleton isolated from Eucalyptus globulus

被引：42
|
作者：
Yin, Sheng [1 ]
Xue, Jun-Juan [1 ]
Fan, Cheng-Qi [1 ]
Miao, Ze-Hong [1 ]
Ding, Jian [1 ]
Yue, Jian-Min [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 26期
关键词：
D O I：
10.1021/ol7025075
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Eucalyptals A-C (1-3) with a new skeleton of 3,5-diformyl-isopentyl phloroglucinol-coupled cadinane were isolated from the fruits of Eucalyptus globulus. Their structures were elucidated by spectroscopic analysis, and that of 1 was confirmed by single-crystal X-ray diffraction. The biosynthetic pathway of 1-3 was also postulated. Compounds 1-3 exhibited selective cytotoxicity against the HL-60 cell line.
引用
收藏
页码：5549 / 5552
页数：4
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