One-pot synthesis of β-amino carbonyl compounds under solvent free condition by using alum doped nanopolyaniline catalyst

Alum doped nanopolyaniline (NDPANI), an efficient and reusable green catalyst for synthesis of beta-amino carbonyl compounds has been developed. Mannich type reaction of various amines, aldehydes and ketones is carried out to synthesize the desire beta-amino carbonyl compounds with excellent yield under solvent free condition. The advantages of this catalyst are inexpensive, reusability, easy preparation and stable. The reaction condition represents an advanced over established method in terms of avoiding solvent, mild reaction condition, clean reaction profile and simple workup.