Clinical role of electrocochleography in children with auditory neuropathy spectrum disorder

被引:15
|
作者
Fontenot, Tatyana E. [1 ]
Giardina, Christopher K. [1 ,2 ]
Teagle, Holly F. [1 ]
Park, Lisa R. [1 ]
Adunka, Oliver F. [3 ]
Buchman, Craig A. [4 ]
Brown, Kevin D. [1 ]
Fitzpatrick, Douglas C. [1 ,2 ]
机构
[1] Univ N Carolina, Dept Otolaryngol, Chapel Hill, NC USA
[2] Univ N Carolina, Sch Med, Chapel Hill, NC USA
[3] Ohio State Univ, Dept Otolaryngol, Columbus, OH 43210 USA
[4] Washington Univ, Dept Otolaryngol, St Louis, MO USA
关键词
Auditory neuropathy spectrum disorder; Cochlear implants; Electrocochleography; Compound action potential; Auditory nerve neurophonic; ROUND WINDOW ELECTROCOCHLEOGRAPHY; SPEECH-PERCEPTION OUTCOMES; COCHLEAR HEARING-LOSS; LANGUAGE OUTCOMES; CHILDHOOD DEVELOPMENT; IMPLANTATION; RECOGNITION; INFANTS; INFORMATION; PREVALENCE;
D O I
10.1016/j.ijporl.2017.05.026
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objectives: To assess electrocochleography (ECochG) to tones as an instrument to account for CI speech perception outcomes in children with auditory neuropathy spectrum disorder (ANSD). Materials & methods: Children (< 18 years) receiving CIs for ANSD (n = 30) and non-ANSD (n = 74) etiologies of hearing loss were evaluated with ECochG using tone bursts (0.25-4 kHz). The total response (TR) is the sum of spectral peaks of responses across frequencies. The compound action potential (CAP) and the auditory nerve neurophonic (ANN) in ECochG waveforms were used to estimate nerve activity and calculate nerve score. Performance on open-set monosyllabic word tests was the outcome measure. Standard statistical methods were applied. Results: On average, TR was larger in ANSD than in non-ANSD subjects. Most ANSD (733%) and non-ANSD (87.8%) subjects achieved open-set speech perception; TR accounted for 33% and 20% of variability in the outcomes, respectively. In the ANSD group, the PTA accounted for 69.3% of the variability, but there was no relationship with outcomes in the non-ANSD group. In both populations, nerve score was sensitive in identifying subjects at risk for not acquiring open-set speech perception, while the CAP and the ANN were more specific. Conclusion: In both subject groups, the TRs correlated with outcomes but these measures were notably larger in the ANSD group. There was also strong correlation between PTA and speech perception outcome in ANSD group. In both subject populations, weaker evidence of neural activity was related to failure to achieve open-set speech perception. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:120 / 127
页数:8
相关论文
共 50 条
  • [1] Intracochlear electrocochleography findings in cochlear implant recipients with auditory neuropathy spectrum disorder
    Ulukan, Merve Bayri
    Ciprut, Ayca
    INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2023, 170
  • [2] Electrocochleography in auditory neuropathy
    Santarelli, R
    Arslan, E
    HEARING RESEARCH, 2002, 170 (1-2) : 32 - 47
  • [3] Vestibular function in children with auditory neuropathy spectrum disorder
    Nash, Robert
    Veness, John
    Wyatt, Michelle
    Raglan, Ewa
    Rajput, Kaukab
    INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2014, 78 (08) : 1269 - 1273
  • [4] Management of children with auditory neuropathy spectrum disorder (ANSD)
    Gokdogan, Cagil
    Altinyay, Senay
    Gunduz, Bulent
    Kemaloglu, Yusuf Kemal
    Bayazit, Yildirim
    Uygur, Kemal
    BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, 2016, 82 (05) : 493 - 499
  • [5] Characteristics and outcomes of children with Auditory Neuropathy Spectrum Disorder
    Barreira-Nielsen, Carmen
    Fitzpatrick, Elizabeth M.
    Whittingham, JoAnne
    CANADIAN JOURNAL OF SPEECH-LANGUAGE PATHOLOGY AND AUDIOLOGY, 2016, 40 (01): : 67 - 79
  • [6] Cochlear Implantation in Children with Auditory Neuropathy Spectrum Disorder
    Teagle, Holly F. B.
    Roush, Patricia A.
    Woodard, Jennifer S.
    Hatch, Debora R.
    Zdanski, Carlton J.
    Buss, Emily
    Buchman, Craig A.
    EAR AND HEARING, 2010, 31 (03): : 325 - 335
  • [7] Imaging Characteristics of Children With Auditory Neuropathy Spectrum Disorder
    Roche, Joseph P.
    Huang, Benjamin Y.
    Castillo, Mauricio
    Bassim, Marc K.
    Adunka, Oliver F.
    Buchman, Craig A.
    OTOLOGY & NEUROTOLOGY, 2010, 31 (05) : 780 - 788
  • [8] Audiological Results in a Group of Children with Auditory Neuropathy Spectrum Disorder
    Mo, Lingyan
    Yan, Fei
    Liu, Hui
    Han, Demin
    Zhang, Luo
    ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES, 2010, 72 (02): : 75 - 79
  • [9] Outcomes of audiometric testing in children with auditory neuropathy spectrum disorder
    Meleca, Joseph B.
    Stillitano, Gina
    Lee, Maxwell Y.
    Lyle, Whitney
    Liu, Yi-Chun Carol
    Anne, Samantha
    INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2020, 129
  • [10] Cortical Auditory Evoked Potential Testing in Children With Auditory Neuropathy Spectrum Disorder
    Morlet, Thierry
    Valania, Jenna
    Walter, Cassidy
    Morini, Giovanna
    O'Reilly, Robert C.
    Parkes, William
    Pritchett, Cedric
    AMERICAN JOURNAL OF AUDIOLOGY, 2024, 33 (01) : 171 - 182