Functional heme oxygenase-1 promoter polymorphism in relation to heart failure and cardiac transplantation

被引：13
|
作者：
Holweg, CTJ
Balk, AHMM
Uitterlinden, AG
Niesters, HGM
Maat, LPWM
Weimar, W
Baan, CC
机构：
[1] Univ Med Ctr, Erasmus MC, Dept Internal Med, Sect Transplantat, NL-3015 GE Rotterdam, Netherlands
[2] Univ Med Ctr, Erasmus MC, Dept Cardiol, NL-3015 GE Rotterdam, Netherlands
[3] Univ Med Ctr, Erasmus MC, Inst Mol Biol, Dept Diagnost, NL-3015 GE Rotterdam, Netherlands
[4] Univ Med Ctr, Erasmus MC, Dept Thorac Surg, NL-3015 GE Rotterdam, Netherlands
来源：
JOURNAL OF HEART AND LUNG TRANSPLANTATION | 2005年 / 24卷 / 04期
关键词：
D O I：
10.1016/j.healun.2004.02.010
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We investigated the functional promoter repeat polymorphism (GT)(n) in the oxidative stress-induced enzyme heme oxygenase-1 in relation to heart failure and complications after transplantation. No influence of the polymorphism on the development of heart failure, graft survival, acute rejection, or transplant atherosclerosis was found. Copyright (c) 2005 by the International Society for Heart and Lung Transplantation.
引用
收藏
页码：493 / 497
页数：5
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