Levels of soluble Fas ligand in myocarditis

被引：54
|
作者：
Toyozaki, T
Hiroe, M
Tanaka, M
Nagata, S
Ohwada, H
Marumo, F
机构：
[1] Tokyo Med & Dent Univ, Dept Med 2, Div Cardiol, Bunkyo Ku, Tokyo 113, Japan
[2] Osaka Univ, Sch Med, Dept Genet, Osaka, Japan
[3] Chiba Univ, Sch Med, Inst Pulm Canc Res, Div Pathol, Chiba 280, Japan
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 1998年 / 82卷 / 02期
关键词：
D O I：
10.1016/S0002-9149(98)00300-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Serum levels of soluble Fas Ligand (sFasL) increased with the severity of congestive heart failure (p <0.01), and the percentages of apoptotic myocytes detected by in situ DNA nick-end labeling were significantly higher in the patients with increased levels of sFasL than in those with normal levels of sFasL (p <0.05). These findings indicated that sFasL may play an important role in pathogenesis of myocarditis.
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页码：246 / +
页数：5
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