Three New Indole-Containing Diketopiperazine Alkaloids from a Deep-Ocean Sediment Derived Fungus Penicillium griseofulvum

被引：45
|
作者：
Zhou, Li-Na [1 ]
Zhu, Tian-Jiao [1 ]
Cai, Sheng-Xin [1 ]
Gu, Qian-Qun [1 ]
Li, De-Hai [1 ]
机构：
[1] Ocean Univ China, Chinese Minist Educ, Sch Med & Pharm, Key Lab Marine Drugs, Qingdao 266003, Peoples R China
来源：
HELVETICA CHIMICA ACTA | 2010年 / 93卷 / 09期
关键词：
ASPERGILLUS; NEOECHINULIN; ASSAY;
D O I：
10.1002/hlca.200900443
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Three new indole-containing diketopiperazine alkaloids, named variecolorins M-O (1-3) together with the eight known analogues 4-11, were isolated from a deep-ocean sediment-derived fungus. Penicillium griseofulvum. Their structures were determined by analysis of the spectroscopic data. The 2,2-diphenyl-1-picrylhydrazinyl (DPPH) radical-scavenging activities and the cell-proliferation inhibitory activities of the three new compounds 1-3 were investigated.
引用
收藏
页码：1758 / 1763
页数：6
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