A supramolecular approach to multivalent target-specific MRI contrast agents for angiogenesis

被引:45
|
作者
Dirksen, A
Langereis, S
de Waal, BFM
van Genderen, MHP
Hackeng, TM
Meijer, EW
机构
[1] Eindhoven Univ Technol, Lab Macromol & Organ Chem, NL-5600 MB Eindhoven, Netherlands
[2] Univ Maastricht, CARIM, NL-6200 MD Maastricht, Netherlands
关键词
D O I
10.1039/b502347e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The synthesis of a cyclic peptide-Gd(III)DTPA molecule equipped with biotin is presented, yielding a well-defined multivalent MRI contrast agent after its coupling to avidin.
引用
收藏
页码:2811 / 2813
页数:3
相关论文
共 50 条
  • [1] A Modular Approach towards the Synthesis of Target-Specific MRI Contrast Agents
    Verwilst, Peter
    Eliseeva, Svetlana V.
    Carron, Sophie
    Elst, Luce Vander
    Burtea, Carmen
    Dehaen, Geert
    Laurent, Sophie
    Binnemans, Koen
    Muller, Robert N.
    Parac-Vogt, Tatjana N.
    De Borggraeve, Wim M.
    EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2011, (24) : 3577 - 3585
  • [2] Synthesis and relaxivity of target-specific MRI contrast agents
    Clement, Callie
    Bradshaw, Joseph
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
  • [3] Peptide derivatized lamellar aggregates as target-specific MRI contrast agents
    Tesauro, Diego
    Accardo, Antonella
    Gianolio, Eliana
    Paduano, Luigi
    Teixeira, Jose
    Schillen, Karin
    Aime, Silvio
    Morelli, Giancarlo
    CHEMBIOCHEM, 2007, 8 (08) : 950 - 955
  • [4] Synthesis, binding affinity, and relaxivity of target-specific MRI contrast agents
    Isaac Zigelboim
    Daniel Offen
    Eldad Melamed
    Hana Panet
    Moshe Rehavi
    Yoram Cohen
    Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2007, 59 : 323 - 329
  • [5] Synthesis, binding affinity, and relaxivity of target-specific MRI contrast agents
    Zigelboim, Isaac
    Offen, Daniel
    Melamed, Eldad
    Panet, Hana
    Rehavi, Moshe
    Cohen, Yoram
    JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 2007, 59 (3-4) : 323 - 329
  • [6] TARGET-SPECIFIC SUPERPARAMAGNETIC MR CONTRAST AGENTS
    WEISSLEDER, R
    MAGNETIC RESONANCE IN MEDICINE, 1991, 22 (02) : 209 - 212
  • [7] Target-specific MRI contrast agents: Cocaine derived probes to visualize DAT
    Naumiec, Gregory R.
    DeBoef, Brenton
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [8] Design and synthesis of target-specific contrast agents
    Dirksen, A
    Langereis, S
    de Waal, BFM
    van Genderen, MHP
    Meijer, EW
    Adriaens, W
    Hackeng, TM
    BIOPOLYMERS, 2005, 80 (04) : 514 - 514
  • [9] Design and synthesis of target-specific contrast agents
    Dirksen, Anouk
    Langereis, Sander
    de Waal, Bas F. M.
    van Genderen, Marcel H. P.
    Meijer, E. W.
    Adriaens, Wencke
    Hackeng, Tilman M.
    UNDERSTANDING BIOLOGY USING PEPTIDES, 2006, : 675 - +
  • [10] Design and synthesis of a bimodal target-specific contrast agent for angiogenesis
    Dirksen, A
    Langereis, S
    de Waal, BFM
    van Genderen, MHP
    Meijer, EW
    de Lussanet, QG
    Hackeng, TM
    ORGANIC LETTERS, 2004, 6 (26) : 4857 - 4860