DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity of flavonoids obtained from some medicinal plants

被引：198
|
作者：
Okawa, M
Kinjo, J
Nohara, T
Ono, M
机构：
[1] Kumamoto Univ, Fac Pharmaceut Sci, Kumamoto 8620973, Japan
[2] Fukuoka Univ, Fac Pharmaceut Sci, Fukuoka 8140180, Japan
[3] Kyushu Tokai Univ, Sch Agr, Kumamoto 8691404, Japan
来源：
BIOLOGICAL & PHARMACEUTICAL BULLETIN | 2001年 / 24卷 / 10期
关键词：
flavonoid; flavone; flavonol; DPPH radical scavenging activity; antioxidative activity; ESR;
D O I：
10.1248/bpb.24.1202
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A reactive oxygen species has been implicated in a range of human pathological diseases such as atherosclerosis and certain cancers. Flavonoids are reported to exhibit various biological activities, including antioxidative and free radical scavenging activities. Several flavonoids obtained from. barley leaves, soybean and some medicinal plants, Silybum marianum, Sophorae Flos, Cinnamon, Ephedrae Herba and Scutellariae Radix, were tested for their DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity. The structure-activity relationships suggested that not only the numbers of hydroxy group but also the position of hydroxy group might be important for mediating potent activity.
引用
收藏
页码：1202 / 1205
页数：4
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