Single Cell Mutation Analysis Delineates Clonal Architecture in Leukemic Transformation of Myeloproliferative Neoplasms

被引：1
|
作者：
Gugliemelli, Paola [1 ]
Calabresi, Laura [1 ]
Carretta, Chiara [2 ]
Rotunno, Giada [1 ]
Parenti, Sandra [2 ]
Romagnoli, Simone [1 ]
Mallia, Selene [2 ]
Bartalucci, Niccolo [1 ]
Rontauroli, Sebastiano [2 ]
Chiereghin, Chiara [3 ]
Castellano, Sara [4 ]
Mannelli, Francesco [1 ]
Della Porta, Matteo G. [5 ,6 ]
Manfredini, Rossella [2 ]
Vannucchi, Alessandro [1 ]
机构：
[1] Univ Florence, Ctr Res & Innovat Myeloproliferat Neoplasms, CRIMM, AOU Careggi, Florence, Italy
[2] Univ Modena & Reggio Emilia, Ctr Regenerat Med S Ferrari, Modena, Italy
[3] IRCCS, Humanitas Clin & Res Ctr, Milan, Italy
[4] Univ Modena & Reggio Emilia, Ctr Genome Res, Modena, Italy
[5] Humanitas Univ, Humanitas Clin & Res Ctr, IRCCS Rozzano, Milan, Italy
[6] Humanitas Univ, Dept Biomed Sci, Milan, Italy
来源：
BLOOD | 2021年 / 138卷
关键词：
D O I：
10.1182/blood-2021-148315
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
56
引用
收藏
页数：3
相关论文
共 50 条
  • [1] SINGLE CELL ANALYSIS OF CLONAL ARCHITECTURE IN LEUKEMIC TRANSFORMATION OF MYELOPROLIFERATIVE NEOPLASMS (MPN)
    Calabresi, L.
    Rotunno, G.
    Mannarelli, C.
    Gesullo, F.
    Romagnoli, S.
    Coltro, G.
    Atanasio, A.
    Vannucchi, A. M.
    Guglielmelli, P.
    HAEMATOLOGICA, 2021, 106 (10) : 65 - 65
  • [2] Clonal dynamics and copy number variants by single-cell analysis in leukemic evolution of myeloproliferative neoplasms
    Calabresi, Laura
    Carretta, Chiara
    Romagnoli, Simone
    Rotunno, Giada
    Parenti, Sandra
    Bertesi, Matteo
    Bartalucci, Niccolo
    Rontauroli, Sebastiano
    Chiereghin, Chiara
    Castellano, Sara
    Gentili, Giulia
    Maccari, Chiara
    Vanderwert, Fiorenza
    Mannelli, Francesco
    Della Porta, Matteo
    Manfredini, Rossella
    Vannucchi, Alessandro Maria
    Guglielmelli, Paola
    AMERICAN JOURNAL OF HEMATOLOGY, 2023, 98 (10) : 1520 - 1531
  • [3] Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms
    Rampal, Raajit
    Ahn, Jihae
    Abdel-Wahab, Omar
    Nahas, Michelle
    Wang, Kai
    Lipson, Doron
    Otto, Geoff A.
    Yelensky, Roman
    Hricik, Todd
    McKenney, Anna Sophia
    Chiosis, Gabriela
    Chung, Young Rock
    Pandey, Suveg
    van den Brink, Marcel R. M.
    Armstrong, Scott A.
    Dogan, Ahmet
    Intlekofer, Andrew
    Manshouri, Taghi
    Park, Christopher Y.
    Verstovsek, Srdan
    Rapaport, Franck
    Stephens, Philip J.
    Miller, Vincent A.
    Levine, Ross L.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (50) : E5401 - E5410
  • [4] Leukemic Transformation of Myeloproliferative Neoplasms: Therapeutic and Genomic Considerations
    Li, Bing
    Mascarenhas, John O.
    Rampal, Raajit K.
    CURRENT HEMATOLOGIC MALIGNANCY REPORTS, 2018, 13 (06) : 588 - 595
  • [5] Leukemic Transformation of Myeloproliferative Neoplasms: Therapeutic and Genomic Considerations
    Bing Li
    John O. Mascarenhas
    Raajit K. Rampal
    Current Hematologic Malignancy Reports, 2018, 13 : 588 - 595
  • [6] Therapeutic options for leukemic transformation in patients with myeloproliferative neoplasms
    Khan, Maliha
    Siddiqi, Rabbia
    Gangat, Naseema
    LEUKEMIA RESEARCH, 2017, 63 : 78 - 84
  • [7] THE ROLE OF JAK2-V617F MUTATION IN LEUKEMIC TRANSFORMATION OF MYELOPROLIFERATIVE NEOPLASMS
    Tevet, M.
    Lupu, A.
    Saguna, C.
    Dragan, C.
    Colita, A.
    Barca, G.
    HAEMATOLOGICA, 2012, 97 : 633 - 633
  • [8] Mutational analysis of BCORL1 in the leukemic transformation of chronic myeloproliferative neoplasms
    Giada Rotunno
    Paola Guglielmelli
    Flavia Biamonte
    Elisa Rumi
    Mario Cazzola
    Alessandro M. Vannucchi
    Annals of Hematology, 2014, 93 : 523 - 524
  • [9] Mutational analysis of BCORL1 in the leukemic transformation of chronic myeloproliferative neoplasms
    Rotunno, Giada
    Guglielmelli, Paola
    Biamonte, Flavia
    Rumi, Elisa
    Cazzola, Mario
    Vannucchi, Alessandro M.
    ANNALS OF HEMATOLOGY, 2014, 93 (03) : 523 - 524
  • [10] Novel Molecular Insights into Leukemic Evolution of Myeloproliferative Neoplasms: A Single Cell Perspective
    Rontauroli, Sebastiano
    Carretta, Chiara
    Parenti, Sandra
    Bertesi, Matteo
    Manfredini, Rossella
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (23)
12345