Molecular cloning and characterisation of a mouse gene encoding an isoform of the neuronal cyclin-dependent kinase 5 (CDK5) activator

被引：9
|
作者：
Nildén, F [1 ]
Bäckström, A [1 ]
Bark, C [1 ]
机构：
[1] Univ Uppsala, BMC, Dept Dev Neurosci, S-75123 Uppsala, Sweden
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1998年 / 1398卷 / 03期
关键词：
CDK5; activator; Cdc2-like protein kinase; neuronal protein; p35; p39; gene;
D O I：
10.1016/S0167-4781(98)00073-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We have isolated and characterised the mouse gene for the p39 activator, designated p39is, which encodes a protein of 369 amino acids. The mouse p39 protein exhibits 95% amino acid identity to a previously characterised human p39 cDNA and the novel gene sequence corresponds to a single genomic locus in mouse. The p39is mRNA is highly expressed in the mouse central nervous system. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：371 / 376
页数：6
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