Estimation of the parameters of the enzymatic reaction and steady-state oxygen distribution in chorioid and retina

The parameters of the ophthalmic artery bed of a patient were reconstructed from X-ray tomography data. Based on these parameters and additional information on the morphology and mode of blood circulation In the chorioid and retinal artery, a mathematical model of blood circulation in the eye, oxygen transfer in blood stream, and oxygen consumption in the enzymic reaction was constructed. Using the model, the steady-state oxygen distribution In the vicinity of the bed is shown and the kinetic parameters of the enzymic reaction of oxygen consumption were estimated.