Effective dose range of candesartan cilexetil for systemic hypertension

被引：19
|
作者：
Bell, TP
DeQuattro, V
Lasseter, KC
Ruff, D
Hardison, JD
Cushing, D
Kezer, AE
Michelson, EL
机构：
[1] Univ S Alabama, Med Ctr, Mobile, AL USA
[2] Univ So Calif, Sch Med, Los Angeles, CA USA
[3] Clin Pharmacol Associates, Miami, FL USA
[4] Healthcare Discoveries, San Antonio, TX USA
[5] Astra Pharmaceut LP, Wayne, PA USA
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 1999年 / 83卷 / 02期
关键词：
D O I：
10.1016/S0002-9149(98)00837-6
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The results of this randomized, double-blind, placebo-controlled, forced-dose titration study in a diverse population of hypertensive patients in the US indicate that candesartan cilexetil has clinically meaningful dose-related blood pressure-lowering effects and that maximum blood pressure reduction is achieved with doses of 16 and 32 mg given once daily. This study confirms that candesartan cilexetil is a highly effective antihypertensive agent with an excellent tolerability and safety profile, without dose-related adverse effects.
引用
收藏
页码：272 / +
页数：5
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