Overexpression of ABCG1 lowers plasma HDL-C and enhances biliary cholesterol and phospholipid secretion in transgenic mice

被引:0
|
作者
Basso, F [1 ]
Amar, MJ [1 ]
Vaisman, B [1 ]
Joyce, C [1 ]
Wu, J [1 ]
Brewer, HB [1 ]
Santamarina-Fojo, S [1 ]
机构
[1] NHLBI, NIH, Bethesda, MD 20892 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1221
引用
收藏
页码:258 / 259
页数:2
相关论文
共 41 条
  • [1] Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet
    Wiersma, Harmen
    Nijstad, Niels
    de Boer, Jan Freark
    Out, Ruud
    Hogewerf, Wytse
    Van Berkel, Theo J.
    Kuipers, Folkert
    Tietge, Uwe J. F.
    ATHEROSCLEROSIS, 2009, 206 (01) : 141 - 147
  • [2] LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL
    Wang, Nan
    Ranalletta, Mollie
    Matsuura, Fumihiko
    Peng, Felix
    Tall, Alan R.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2006, 26 (06) : 1310 - 1316
  • [3] Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and inhibits cholesterol absorption in mice
    Yu, LQ
    Jia, LH
    Hammer, RE
    Berge, KE
    Horton, JD
    Cohen, J
    Hobbs, HH
    CIRCULATION, 2002, 106 (19) : 73 - 73
  • [4] Contribution of hepatic and extrahepatic ABCA1 to plasma HDL-C and apoB-containing lipoprotein cholesterol in transgenic mice
    Liu, LJ
    Joyce, C
    Vaisman, B
    Basso, F
    Amar, MJ
    Shamburek, RD
    Santamarina-Fojo, S
    CIRCULATION, 2005, 112 (17) : U226 - U226
  • [5] ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet
    Terasaka, Naoki
    Yu, Shuiqing
    Yvan-Charvet, Laurent
    Wang, Nan
    Mzhavia, Nino
    Langlois, Read
    Pagler, Tamara
    Li, Rong
    Welch, Carrie L.
    Goldberg, Ira J.
    Tall, Alan R.
    JOURNAL OF CLINICAL INVESTIGATION, 2008, 118 (11): : 3701 - 3713
  • [6] Human ABCA1 transgenic mice: Hepatic and macrophage expression of ABCA1 increases plasma HDL concentrations and enhances biliary cholesterol excretion
    Joyce, C
    Vaisman, BL
    Amar, MJ
    Lambert, G
    Fruchart-Najib, J
    Neufeld, EB
    Remaley, AT
    Shamburek, RD
    Brewer, HB
    Santamarina-Fojo, S
    CIRCULATION, 2001, 104 (17) : 148 - 149
  • [7] Hepatic HDL cholesterol uptake, VLDL production and biliary lipid secretion in human CETP transgenic mice
    Quintao, ECR
    Harada, LM
    Amigo, L
    Cazita, PM
    Salerno, AG
    Rigotti, A
    Oliveira, HCF
    ATHEROSCLEROSIS SUPPLEMENTS, 2005, 6 (01) : 54 - 54
  • [8] ABCA1, ABCG1 AND SCARB1 GENE EXPRESSION ANALYSES IN ASYMPTOMATIC SUBJECTS WITH HIGH AND LOW HDL-C
    Zago, V. H. S.
    Scherrer, D. Z.
    Parra, E. S.
    Panzoldo, N. B.
    Vendrame, F.
    Quintao, E. C. R.
    de Faria, E. C.
    ATHEROSCLEROSIS, 2014, 235 (02) : E135 - E135
  • [9] Overexpression of human ABCG5 and ABCG8 in transgenic mice: Effects on intestinal cholesterol absorption, biliary sterol excretion and atherosclerosis
    Wu, JE
    Basso, F
    Shamburek, RD
    Amar, MJ
    Vaisman, B
    Tansey, T
    Lita, F
    Paigen, B
    Fruchart-Najib, J
    Brewer, HB
    Santamarina-Fojo, S
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (05) : A42 - A43
  • [10] ABCG1 overexpressed in HEK293 cells is localized to sub-cellular organelles and enhances cholesterol efflux to HDL
    Lee, RG
    Tarr, P
    Baldan, A
    Edwards, PA
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2006, 26 (05) : E55 - E55