The real cost of sequencing: higher than you think!

被引：228
|
作者：
Sboner, Andrea [1 ,2 ]
Mu, Xinmeng Jasmine [1 ]
Greenbaum, Dov [1 ,2 ,3 ,4 ,5 ]
Auerbach, Raymond K. [1 ]
Gerstein, Mark B. [1 ,2 ,6 ]
机构：
[1] Yale Univ, Program Computat Biol & Bioinformat, New Haven, CT 06520 USA
[2] Yale Univ, Dept Mol Biol & Biophys, New Haven, CT 06520 USA
[3] Sanford T Colb & Co, Intellectual Property Law, IL-76122 Rehovot, Israel
[4] Stanford Univ, Stanford Law Sch, Ctr Law & Biosci, Stanford, CA 94305 USA
[5] Kiryat Ono Coll, Sholar Residence Ctr Hlth Law Bioeth & Hlth Polic, IL-55000 Tel Aviv, Israel
[6] Yale Univ, Dept Comp Sci, New Haven, CT 06520 USA
来源：
GENOME BIOLOGY | 2011年 / 12卷 / 08期
基金：
美国国家卫生研究院;
关键词：
Bioinformatics; costs of sequencing; data analysis; experimental design; next-generation sequencing; sample collection; GENOME; DISCOVERY;
D O I：
10.1186/gb-2011-12-8-125
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Advances in sequencing technology have led to a sharp decrease in the cost of 'data generation'. But is this sufficient to ensure cost-effective and efficient 'knowledge generation'?
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页数：10
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