The catalytic subunit of DNA-PK has a unique function in inflammation independently of Ku70 and DNA repair: a new opportunity to target the enzyme without interfering with DNA repair

被引：0
|
作者：
Ghonim, Mohamed Ahmed [1 ,2 ]
Pyakurel, Kusma [1 ]
Luu, Hanh [1 ]
Okpechi, Samuel [1 ]
Ju, Jihang [1 ]
Boulares, Hamid [1 ]
机构：
[1] Louisiana State Univ, Hlth Sci Ctr, Baton Rouge, LA 70803 USA
[2] Al Azhar Univ, Fac Pharm, Dept Microbiol & Immunol, Cairo, Egypt
来源：
JOURNAL OF IMMUNOLOGY | 2018年 / 200卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
173.18
引用
收藏
页数：3
相关论文
共 22 条
  • [1] The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation
    Liu, Jia
    Naegele, Janice R.
    Lin, Stanley L.
    BRAIN RESEARCH, 2009, 1296 : 164 - 175
  • [2] Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK
    Hanakahi, LA
    West, SC
    EMBO JOURNAL, 2002, 21 (08): : 2038 - 2044
  • [3] Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
    TimTakKwok
    SiuKaiKong
    BenjaminChen
    DavidJChen
    CellResearch, 2007, (02) : 100 - 116
  • [4] Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
    Fang, Longhou
    Wang, YiGuo
    Du, Dan
    Yang, Guang
    Kwok, Tim Tak
    Kong, Siu Kai
    Chen, Benjamin
    Chen, David J.
    Chen, Zhengjun
    CELL RESEARCH, 2007, 17 (02) : 100 - 116
  • [5] Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
    Longhou Fang
    YiGuo Wang
    Dan Du
    Guang Yang
    Tim Tak Kwok
    Siu Kai Kong
    Benjamin Chen
    David J Chen
    Zhengjun Chen
    Cell Research, 2007, 17 : 100 - 116
  • [6] Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
    Longhou Fang
    YiGuo Wang
    Dan Du
    Guang Yang
    Tim Tak Kwok
    Siu Kai Kong
    Benjamin Chen
    David J Chen
    Zhengjun ChenKey Laboratory of Proteomics and Laboratory of Molecular Cell Biology
    Cell Research, 2007, (06) : 572 - 574
  • [7] Erratum: Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
    Longhou Fang
    YiGuo Wang
    Dan Du
    Guang Yang
    Tim Tak Kwok
    Siu Kai Kong
    Benjamin Chen
    David J Chen
    Zhengjun Chen
    Cell Research, 2007, 17 : 572 - 574
  • [8] The Ku70 DNA-repair protein is involved in centromere function in a grasshopper species
    Cabrero, Josefa
    Bakkali, Mohammed
    Navarro-Dominguez, Beatriz
    Ruiz-Ruano, Francisco J.
    Martin-Blazquez, Ruben
    Dolores Lopez-Leon, Maria
    Camacho, Juan Pedro M.
    CHROMOSOME RESEARCH, 2013, 21 (04) : 393 - 406
  • [9] The Ku70 DNA-repair protein is involved in centromere function in a grasshopper species
    Josefa Cabrero
    Mohammed Bakkali
    Beatriz Navarro-Domínguez
    Francisco J. Ruíz-Ruano
    Rubén Martín-Blázquez
    María Dolores López-León
    Juan Pedro M. Camacho
    Chromosome Research, 2013, 21 : 393 - 406
  • [10] Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK
    Das, Benu Brata
    Antony, Smitha
    Gupta, Shalu
    Dexheimer, Thomas S.
    Redon, Christophe E.
    Garfield, Susan
    Shiloh, Yosef
    Pommier, Yves
    EMBO JOURNAL, 2009, 28 (23): : 3667 - 3680
123