GENOTYPE-BASED IN VITRO-IN VIVO EXTRAPOLATION (IVIVE) OF EFAVIRENZ PHARMACOKINETICS USING A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL

被引：0
|
作者：
Xu, C. [1 ]
Quinney, S. [2 ]
Guo, Y. [3 ]
Desta, Z. [1 ]
机构：
[1] Indiana Univ Sch Med, Div Clin Pharmacol, Indianapolis, IN USA
[2] Indiana Univ Sch Med, Dept Obstet & Gynecol, Indianapolis, IN USA
[3] Lilly Res Labs, Indianapolis, IN USA
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 2012年 / 91卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：S30 / S30
页数：1
相关论文
共 50 条
  • [1] Analysis of Time-Dependent Pharmacokinetics Using In Vitro-In Vivo Extrapolation and Physiologically Based Pharmacokinetic Modeling
    Kim, Min-Chang
    Lee, Young-Joo
    PHARMACEUTICS, 2022, 14 (12)
  • [2] Transporter-based in vitro-in vivo extrapolation (IVIVE)
    Lukacova, Viera
    Bolger, Michael B.
    Woltosz, Walter
    Parrott, Neil
    Poirier, Agnes
    Lave, Thierry
    DRUG METABOLISM REVIEWS, 2011, 43 : 210 - 211
  • [3] Physiologically based approaches towards the prediction of pharmacokinetics:: in vitro-in vivo extrapolation
    De Buck, Stefan S.
    Mackie, Claire E.
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2007, 3 (06) : 865 - 878
  • [4] Predictive performance of physiologically based kinetic (PBK) models based on in-silico/in vitro-in vivo extrapolation (IS/IVIVE)
    Kalra, P.
    Zhou, H.
    Lawless, M.
    TOXICOLOGY LETTERS, 2023, 384 : S259 - S260
  • [5] Predictive performance of physiologically based kinetic (PBK) models based on in-silico/in vitro-in vivo extrapolation (IS/IVIVE)
    Kalra, P.
    Zhou, H.
    Lawless, M.
    TOXICOLOGY LETTERS, 2024, 399 : S125 - S126
  • [6] PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL OF TOPOTECAN TO VERIFY EFFLUX TRANSPORTER IN VITRO IN VIVO EXTRAPOLATION.
    Ning, M.
    Fang, Z.
    Hoeckels-Messemer, J.
    Riedmaier, A. Emami
    Bow, D. A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2019, 105 : S64 - S65
  • [7] Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an In Vitro-In Vivo Extrapolation Model
    Siccardi, M.
    Almond, L.
    Schipani, A.
    Csajka, C.
    Marzolini, C.
    Wyen, C.
    Brockmeyer, N. H.
    Boffito, M.
    Owen, A.
    Back, D.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2012, 92 (04) : 494 - 502
  • [8] CYP2B6 Pharmacogenetics-Based In Vitro-In Vivo Extrapolation of Efavirenz Clearance by Physiologically Based Pharmacokinetic Modeling
    Xu, Cong
    Quinney, Sara K.
    Guo, Yingying
    Hall, Stephen D.
    Li, Lang
    Desta, Zeruesenay
    DRUG METABOLISM AND DISPOSITION, 2013, 41 (12) : 2004 - 2011
  • [9] Species Extrapolation of Life-Stage Physiologically-Based Pharmacokinetic (PBPK) Models to Investigate the Developmental Toxicology of Ethanol Using In vitro to In vivo (IVIVE) Methods
    Martin, Sheppard A.
    McLanahan, Eva D.
    Bushnell, Philip J.
    Hunter, E. Sidney, III
    El-Masri, Hisham
    TOXICOLOGICAL SCIENCES, 2015, 143 (02) : 512 - 535
  • [10] Using physiologically based pharmacokinetic modelling for in silico-in vitro-in vivo extrapolation to predict chemical exposure
    Lawless, M.
    Zhou, H.
    Fraczkiewicz, G.
    TOXICOLOGY LETTERS, 2016, 258 : S119 - S120
12345