Synthesis and biological activity of new trisubstituted pyrimidine phenylsulfonylurea derivatives

被引：0

作者：

Guo Wan-Cheng ^{[1
]}

Tan Hai-Zhong ^{[1
]}

Liu Xing-Hai ^{[1
]}

Li Yong-Hong ^{[1
]}

Wang Su-Hua ^{[1
]}

Li Zheng-Ming ^{[1
]}

机构：

[1] Nankai Univ, Inst Elementoorgan Chem, Nat Pesticide Engn Res Ctr, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2008年 / 29卷 / 02期

关键词：

sulfonylurea; pyrimidine; herbicidal activity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In order to develop new herbicidal active compounds and research the structure-activity relationship, twenty-two new sulfonylurea derivatives with trisubstituting group in the pyrimidine ring were designed and synthesized. Their structures were confirmed by H-1 NMR, MS and elemental analysis. Preliminary herbicidal activity of these new sulfonylurea compounds was determined by pot bioassay experiments at dosage of 1.5 kg/ha. The results show that these trisubstituted pyrimidine phenylsulfonylurea derivatives display weak heribicidal activity and the addition of 5-substituting group of the pyrimidine ring affected the herbicidal activity slightly.

引用

页码：319 / 323

页数：5

共 9 条

[1] ACETOLACTATE SYNTHASE IS THE SITE OF ACTION OF 2 SULFONYLUREA HERBICIDES IN HIGHER-PLANTS
CHALEFF, RS
MAUVAIS, CJ
[J]. SCIENCE, 1984, 224 (4656) : 1443 - 1445
[2] Duggleby RG, 2000, J BIOCHEM MOL BIOL, V33, P1
[3] GERORGE L, 1983, Patent No. 4394506
[4] LAROSSA RA, 1984, J BIOL CHEM, V259, P8753
[5] LEVITT G, 1991, ACS SYM SER, V443, P16
[6] Li PF, 2005, CHEM J CHINESE U, V26, P1459
[7] LIU CL, 2005, DESIGN SYNTHESIS BIO
[8] MA N, 2004, THESIS COLL CHEM TIA
[9] SITE OF ACTION OF CHLORSULFURON - INHIBITION OF VALINE AND ISOLEUCINE BIOSYNTHESIS IN PLANTS
RAY, TB
[J]. PLANT PHYSIOLOGY, 1984, 75 (03) : 827 - 831

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