A high yielding, one-pot synthesis of substituted ureas from the corresponding amines using Mitsunobu's reagent

被引:21
|
作者
Chaturvedi, Devdutt [1 ]
Mishra, Nisha [2 ]
Mishra, Virendra [2 ]
机构
[1] Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226001, Uttar Pradesh, India
[2] BSA Coll, Dept Chem, Synthet Res Lab, Mathura, Uttar Pradesh, India
来源
MONATSHEFTE FUR CHEMIE | 2008年 / 139卷 / 03期
关键词
Mitsunobu's reagent; carbon dioxide; amines; substituted ureas;
D O I
10.1007/s00706-007-0776-1
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A Mitsunobu-based protocol has been developed for the synthesis of symmetrically and unsymmetrically substituted ureas from a variety of primary and secondary amines using gaseous carbon dioxide, in good to excellent yields. This protocol is mild and efficient compared to other reported methods.
引用
收藏
页码:267 / 270
页数:4
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