Ultrasound Findings in Fetal Congenital Heart Block Associated With Maternal Anti-Ro/SSA and Anti-La/SSB Antibodies

被引：5
|
作者：
Lai, Jasmine [1 ]
Clark, Toshi J. [2 ]
Tan, Justin H. [3 ]
Delaney, Shani [1 ]
Jolley, Jennifer A. [1 ]
机构：
[1] Univ Washington, Med Ctr, Dept Obstet & Gynecol, Div Maternal Fetal Med, Seattle, WA 98195 USA
[2] Univ Washington, Med Ctr, Dept Radiol, Div Body Imaging, Seattle, WA 98195 USA
[3] Univ Calif San Diego, San Diego Med Ctr, Dept Radiol, San Diego, CA 92103 USA
来源：
ULTRASOUND QUARTERLY | 2015年 / 31卷 / 01期
关键词：
fetal congenital heart block; neonatal lupus erythematosus; fetal bradyarrhythmia; NEONATAL LUPUS; CARDIAC MANIFESTATIONS; ATRIOVENTRICULAR-BLOCK; RECURRENCE RATES; RISK; HYDROXYCHLOROQUINE; MORBIDITY; MORTALITY; REGISTRY;
D O I：
10.1097/RUQ.0000000000000112
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We present the sonographic features of a second-trimester fetus diagnosed with a bradyarrhythmia at 19 weeks' gestation. The mother carried a diagnosis of Sjogren syndrome, including the presence of SSA and SSB antibodies. Ultrasound M-mode and fetal echocardiogram revealed the etiology of the bradycardia to be a complete fetal congenital heart block, likely due to transplacental passage of autoimmune anti-Ro/SSA and anti-La/SSB antibodies. Consequential to the congenital heart block, the fetus developed hydrops fetalis at 21 weeks' gestational age. We discuss the 2 major etiologies of congenital heart block and the implications in subsequent pregnancies.
引用
收藏
页码：34 / 36
页数：3
相关论文
共 50 条
  • [1] Maternal Anti-Ro/SSA and Anti-La/SSB Antibodies and Fetal Congenital Heart Block
    Kapur A.
    Dey M.
    Tangri M.
    Bandhu H.C.
    The Journal of Obstetrics and Gynecology of India, 2015, 65 (3) : 193 - 195
  • [2] Anti-Ro (SSA) and anti-La (SSB) antibodies and complete congenital heart block
    Finkelstein, Y
    Adler, Y
    Harel, L
    Nussinovitch, M
    Youinou, P
    ANNALES DE MEDECINE INTERNE, 1997, 148 (03): : 205 - 208
  • [3] CONGENITAL HEART BLOCK IN A COHORT OF PREGNANT WOMEN WITH ANTI-RO/SSA AND/OR ANTI-LA/SSB ANTIBODIES
    Palasti, S. M.
    Dominguez, V.
    Masoller, N.
    Ramirez, J. C.
    Teixido, I.
    Cervera, R.
    Figueras, F.
    Espinosa, G.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 72 : 481 - 481
  • [4] Transient heart block in a neonate associated with previously undiagnosed maternal anti-Ro/SSA and anti-La/SSB antibodies
    Escamilla, S. A.
    Pettersen, M. D.
    PEDIATRIC CARDIOLOGY, 2007, 28 (03) : 221 - 223
  • [5] Transient Heart Block in a Neonate Associated with Previously Undiagnosed Maternal Anti-Ro/SSA and Anti-La/SSB Antibodies
    S.A. Escamilla
    M.D. Pettersen
    Pediatric Cardiology, 2007, 28 : 221 - 223
  • [6] Subclass distribution of maternal and neonatal Anti-Ro(SSA) and La(SSB) antibodies in congenital heart block
    Tseng, CE
    Caldwell, K
    Feit, S
    Chan, EKL
    Buyon, JP
    JOURNAL OF RHEUMATOLOGY, 1996, 23 (05) : 925 - 932
  • [7] Anti-Ro/SSA and/or anti-La/SSB antibodies are associated with adverse endometrial status
    Lu, Fangting
    Wang, Yanshi
    Fang, Xuhui
    Jin, Rentao
    Xu, Bo
    Qiu, Qiannan
    Wu, Li
    AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2023, 89 (06)
  • [8] On the article of Y. Finkelstein and collaborators: "Anti-Ro (SSA) and anti-La (SSB) antibodies and complete congenital heart block"
    Herreman, G
    ANNALES DE MEDECINE INTERNE, 1997, 148 (08): : 582 - 582
  • [9] ANTI-RO(SSA) AND ANTI-LA(SSB) ANTIBODIES IN AUTOIMMUNE RHEUMATIC DISEASES
    YOUINOU, P
    ADLER, Y
    MULLER, S
    LAMOUR, A
    BARON, D
    HUMBEL, RL
    CLINICAL REVIEWS IN ALLERGY, 1994, 12 (03): : 253 - 274
  • [10] Anti-Ro/SSA and/or anti-La/SSB antibodies are associated with adverse IVF and pregnancy outcomes
    Fang, Xuhui
    Lu, Fangting
    Wang, Yanshi
    Guo, Lan
    Zhang, Yu
    Bai, Shun
    Kwak-Kim, Joanne
    Wu, Li
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2022, 149
12345