Head and Neck Cancer Research and Support Foundations

被引：9
|
作者：
Lubek, Joshua E. [1 ]
机构：
[1] Univ Maryland, Dept Oral & Maxillofacial Surg, Oral Head & Neck Surg Microvasc Surg, 650 West Baltimore St,Suite 1401, Baltimore, MD 21201 USA
来源：
ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA | 2018年 / 30卷 / 04期
关键词：
Head and neck cancer research; Dysplasia; Immunotherapy; Xerostomia; Cancer organizations; SQUAMOUS-CELL CARCINOMA; HUMAN-PAPILLOMAVIRUS VACCINATION; POTENTIALLY MALIGNANT DISORDERS; SALIVARY-GLAND HYPOFUNCTION; TRANSORAL ROBOTIC SURGERY; ORAL-CAVITY; CLINICAL-TRIALS; INSTITUTE HEAD; STEM-CELLS; IFN-GAMMA;
D O I：
10.1016/j.coms.2018.06.007
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Ongoing genetic and epigenetic research involving DNA methylation, salivary bio-markers, wild-type p53 tumor suppressor gene proteins, and HPV oncogenes are being directed at identification and treatment of dysplastic and malignant squamous cell mucosal lesions. Research is being conducted to improve immunotherapy drug response rates by increasing the amount of inflammation within the tumor micro-environment. Ongoing research is focused on the application of the antidiabetic drug metformin for the prevention and management of oral squamous cell dysplastic lesions. Professional and nonprofit cancer support organizations are essential for furthering education and research within the area of head and neck cancer.
引用
收藏
页码：459 / +
页数：12
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