Proton-Pump Inhibitor as Palliative Care for Chemotherapy-Induced Gastroesophageal Reflux Disease in Pancreatic Cancer Patients

被引：11

作者：

Uwagawa, Tadashi ^{[1
]}

Misawa, Takeyuki ^{[1
]}

Iida, Tomonori ^{[1
]}

Sakamoto, Taro ^{[1
]}

Gocho, Takeshi ^{[1
]}

Wakiyama, Shigeki ^{[1
]}

Hirohara, Shoichi ^{[1
]}

Yanaga, Katsuhiko ^{[1
]}

机构：

[1] Jikei Univ, Sch Med, Dept Surg, Tokyo, Japan

来源：

JOURNAL OF PALLIATIVE MEDICINE | 2010年 / 13卷 / 07期

关键词：

RECOMMENDATIONS; GUIDELINES; THERAPY;

D O I：

10.1089/jpm.2009.0404

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Relief of adverse events induced by chemotherapy is an important issue for patients, especially those with a poor prognosis, such as with pancreatic cancer. There are no reports of the relationship between gastroesophageal reflux disease (GERD) and chemotherapy, so we investigated the incidence of chemotherapy-induced GERD in patients undergoing treatment with gemcitabine or S-1 for pancreatic cancer and the effect of sodium rabeprazole (RPZ), a proton-pump inhibitor. GERD was diagnosed in 40% of the patients according to the Frequency Scale for Symptoms of GERD score, and RBZ therapy significantly improved their symptoms.

引用

页码：815 / 818

页数：4

共 50 条

[1] Limited Ability of the Proton-Pump Inhibitor Test to Identify Patients With Gastroesophageal Reflux Disease
Bytzer, Peter
Jones, Roger
Vakil, Nimish
Junghard, Ola
Lind, Tore
Wernersson, Borje
Dent, John
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2012, 10 (12) : 1360 - 1366
[2] Proton-pump inhibitor therapy for gastroesophageal reflux disease - Does it treat the asthma?
Jain, S
CHEST, 2005, 127 (04) : 1097 - 1098
[3] Persistent gastroesophageal reflux disease symptoms on standard proton-pump inhibitor therapy
Sontag, SJ
GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2002, 31 (04) : S77 - +
[4] COST BURDEN OF INAPPROPRIATE PROTON-PUMP INHIBITOR USE AMONG GASTROESOPHAGEAL REFLUX DISEASE PATIENTS
Rane, P.
Guha, S.
Garey, K.
Chen, H.
Johnson, M. L.
Aparasu, R.
VALUE IN HEALTH, 2016, 19 (03) : A314 - A314
[5] The role of proton-pump inhibitor therapy in patients with gastroesophageal reflux disease and difficult-to-control asthma
Goh, Khean-Lee
Wong, Choon-Heng
EXPERT OPINION ON PHARMACOTHERAPY, 2006, 7 (15) : 2015 - 2017
[6] The proton-pump inhibitor test in identifying gastroesophageal reflux disease-related globus
Sinn, Deng Hyun
Rhee, Poong-Iyul
Lee, Jun Haeng
Son, Hee Jung
Chang, Dong Kyung
Kim, Young-Ho
Kim, Jae J.
Rhee, Jong Chul
GASTROENTEROLOGY, 2007, 132 (04) : A287 - A287
[7] Economic Impact of Proton-Pump Inhibitors in Patients With Refractory Gastroesophageal Reflux Disease: A Managed Care Perspective
Fu, An-Chen
Mody, Reema
Gerson, Lauren B.
Tan, Hiangkiat
GASTROENTEROLOGY, 2013, 144 (05) : S205 - S205
[8] A proton-pump inhibitor, rabeprazole, improves ventilatory function in patients with asthma associated with gastroesophageal reflux
Tsugeno, H
Mizuno, M
Fujiki, S
Okada, H
Okamoto, M
Hosaki, Y
Ashida, S
Mitsunobu, F
Tanizaki, Y
Shiratori, Y
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2003, 38 (05) : 456 - 461
[9] Proton-pump inhibitor therapy in patients with gastro-oesophageal reflux disease
Fass, Ronnie
DRUGS, 2007, 67 (11) : 1521 - 1530
[10] Assessment of columnar-lined esophagus in controls and patients with gastroesophageal reflux disease with and without proton-pump inhibitor therapy
I. Mesteri
J. Lenglinger
L. Beller
S. Fischer-See
Sebastian F. Schoppmann
F. Wrba
F. M. Riegler
J. Zacherl
European Surgery, 2012, 44 : 304 - 313

← 1 2 3 4 5 →