Multiple Instance Learning with Genetic Pooling for medical data analysis

Multiple Instance Learning is a weakly supervised learning technique which is particularly well suited for medical data analysis as the class labels are often not available at desired granularity. Multiple Instance Learning through Deep Neural Networks is relatively a new paradigm in machine learning. The most important part of Multiple Instance Learning through Deep Neural Networks is designing a trainable pooling function which determines the instance-to bag relationship. In this paper, we propose a Multiple Instance pooling technique based on Genetic Algorithm called Genetic Pooling. In this technique, instance labels inside a bag are optimized by minimizing bag-level losses. The main contribution of the paper is that the bag level pooling layer for generating attention weights for bag instances are replaced by random initialization of attention weights and finding the optimized attention weights through Genetic Algorithm. (C) 2020 Elsevier B.V. All rights reserved.