Quantitative Health Risk Assessment of the Chronic Inhalation of Chemical Compounds in Healthcare and Elderly Care Facilities

被引:9
|
作者
Colas, Anais [1 ,2 ]
Baudet, Alexandre [2 ,3 ,4 ]
Le Cann, Pierre [5 ]
Blanchard, Olivier [5 ]
Gangneux, Jean-Pierre [5 ,6 ]
Baures, Estelle [5 ]
Florentin, Arnaud [1 ,2 ,4 ]
机构
[1] Univ Lorraine, Fac Med, F-54505 Vandoeuvre Les Nancy, France
[2] CHRU Nancy, F-54505 Vandoeuvre Les Nancy, France
[3] Univ Lorraine, Fac Dodontol, F-54505 Vandoeuvre Les Nancy, France
[4] Univ Lorraine, APEMAC, F-54505 Vandoeuvre Les Nancy, France
[5] Univ Rennes, EHESP Sch Publ Hlth, IRSET Inst Rech Sante Environm & Travail, UMR S 1085,Inserm, F-35000 Rennes, France
[6] CHU Rennes, Lab Parasitol Mycol, F-35000 Rennes, France
关键词
health risk assessment; indoor air pollution; chronic inhalation; chemical compounds; healthcare facility; hospital; nursing home; VOLATILE ORGANIC-COMPOUNDS; INDOOR AIR-QUALITY; RESPIRATORY HEALTH; EXPOSURE; POLLUTANTS;
D O I
10.3390/toxics10030141
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Previous studies have described the chemical pollution in indoor air of healthcare and care facilities. From these studies, the main objective of this work was to conduct a quantitative health risk assessment of the chronic inhalation of chemical compounds by workers in healthcare and elderly care facilities (hospitals, dental and general practitioner offices, pharmacies and nursing homes). The molecules of interest were 36 volatile and 13 semi-volatile organic compounds. Several professional exposure scenarios were developed in these facilities. The likelihood and severity of side effects that could occur were assessed by calculating the hazard quotient for deterministic effects, and the excess lifetime cancer risk for stochastic effects. No hazard quotient was greater than 1. Three compounds had a hazard quotient above 0.1: 2-ethyl-1-hexanol in dental and general practitioner offices, ethylbenzene and acetone in dental offices. Only formaldehyde presented an excess lifetime cancer risk greater than 1 x 10(-5) in dental and general practitioner offices (maximum value of 3.8 x 10(-5) for general practitioners). The health risk for chronic inhalation of most compounds investigated did not appear to be of concern. Some values tend to approach the acceptability thresholds justifying a reflection on the implementation of corrective actions such as the installation of ventilation systems.
引用
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页数:13
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