Autoxidative Carbon-Carbon Bond Formation from Carbon-Hydrogen Bonds

被引：186
|
作者：
Pinter, Aron [1 ]
Sud, Abhishek [1 ]
Sureshkumar, Devarajulu [1 ]
Klussmann, Martin [1 ]
机构：
[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 29期
关键词：
autoxidation; C-H activation; cross-coupling; green chemistry; homogeneous catalysis; FUNCTIONALIZATION; DERIVATIVES; ANTAGONISTS; ACTIVATION; CHEMISTRY; AMINES;
D O I：
10.1002/anie.201000711
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) Only oxygen and acid! The oxidative coupling of xanthene and other activated benzylic compounds with carbon nucleophiles such as ketones, can be performed under ambient conditions without solvent by simply using oxygen and catalytic amounts of methanesulfonic acid. The proposed reaction mechanism involves substrate activation by formation of hydroperoxides; the method can therefore be regarded as an "autoxidative coupling reaction". © 2010 Wiley-VCH Verlag GmbH & Co. KCaA, Weinheim.
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页码：5004 / 5007
页数：4
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